Whole-body health starts in the gut.
Formulas designed to target every area of gut health, developed with doctors ◊ and priced for every day. Shop all products →
60 Billion Probiotic
🦠
⚡
🛡️
Digestive Enzymes
🍕
🔥
😌
Women's Probiotic
🌸
✨
🛡️
Fiber Gummies
🍬
🌿
⏰
What's your gut telling you?
Pick the goals that matter to you, and we'll match you with the right products. Subscribe and save up to 15% on all orders.
250,000+ happy guts, on the record.
""Finally a probiotic that actually survives and works. My digestion has never been this regular — worth every penny.""
""The post-dinner bloat is just… gone. I take one and actually enjoy the meal.""
""I pop one before anything my stomach disagrees with. It has helped me so much.""
""Recommended by my dietician — a total lifesaver.""
""Two weeks in and my whole routine changed. I actually look forward to taking it.""
Not just a probiotic.
A whole-gut upgrade.‡
Better digestion ‡
+Acid-resistant delivery gets the strains past your stomach intact, where they help ease the gas and bloat that follow your favorite meals.‡
Less bloating ‡
+60 billion CFUs across 10 clinically studied strains help break down what you eat and absorb what you need — daily support your gut can actually feel.
Regular, reliably ‡
+Prebiotic fiber feeds the good bacteria in your gut to help keep things moving like clockwork, without the drama.‡
Immune support ‡
+About 70% of your immune system lives in the gut. A balanced microbiome is the foundation the rest of your health is built on.‡
Trust your gut to the experts.
MDs, PhDs, and NDs review the evidence behind every formula we make.
7
Physicians & PhDs8
Specialties, gastro to OB/GYN100%
Of formulas & articles reviewed
MD, PHD
MD
ND
MD, ND
ND
FMN, LN, CN
Questions? Let our Scientific Advisory Board help.
Straight answers from the same board that reviews every formula.
Why should I take a probiotic?
+I strongly recommend that most people incorporate a probiotic supplement into their daily routine. Probiotics offer a wide range of benefits for gut health, hormone health, and immune function.
The foundation of good health starts in the gut.
Dr. Jennifer Roelands, MD
· OB/GYN, Integrative Medicine
When should I take a probiotic?
+Want to maximize your probiotic’s effectiveness? Take it on an empty stomach! Physician’s Choice probiotics are specially formulated with an acid-resistant capsule to ensure that the strains make it to the gut where they can do their job.
Angela Pifer, FMN, LN, CN
· Functional Medicine Nutritionist
What are CFUs and do they matter?
+Each CFU represents a live microbe that can reproduce and form colonies within the digestive system, which is essential for probiotics to work effectively. The CFU count, or "dose," shows the strength of the probiotic, but it’s important to choose the right amount based on the specific health benefits desired. Research indicates that higher CFU counts may offer more advantages for certain strains and purposes. However, more isn’t always better; different health goals require different CFU levels.
Selecting a probiotic involves more than just looking at CFU numbers. Factors such as strain quality, delivery method, and stability during storage all contribute to a probiotic’s effectiveness. Consulting a healthcare professional can help you choose a CFU count and formulation that align with your health goals, maximizing the benefits of probiotic use.
Dr. Thiago Cavalcante, MD, ND ·
· ENT & Naturopathic Doctor
What should I look for in a probiotic?
+When selecting a probiotic supplement, look for one that contains a diverse array of well-researched probiotic strains, such as Lactobacillus and Bifidobacterium species. The potency, or colony-forming units (CFUs), should be at least 10 billion CFUs per serving. Additionally, choose a supplement that is shelf-stable and free of fillers or artificial ingredients.
Dr. Jennifer Roelands, MD
· OB/GYN, Integrative Medicine
What can I expect when starting a probiotic?
+It will depend a bit on the person and what is going on for them, bowel health-wise. If you experience occasional constipation or loose bowels, odds are high that they will start to regulate and be more normally consistent. If you have some bad bacteria in your gut, you may have a bit of a 'die-off' reaction as you introduce a lot of good bacteria in. This may present as some bloating, gas, and irregularity with your bowels. But within a couple weeks, this should very likely subside. And then, you should just be feeling better overall. Digestion should be a process that largely goes unnoticed. What I mean by that is that you shouldn't really feel much of anything 'happening'--it should work like clockwork without a lot of intervention or effort. Some people will notice an improvement in mental clarity and overall mood.
Naturopathic Doctor, ND
· Naturopathic Doctor
How does the subscription work?
+Your routine ships automatically each month at 20% off with free shipping included. You stay in full control: skip a month, swap products, change your delivery date, or cancel anytime in two clicks — no phone calls, no hoops, and no long-term commitment. It's the easiest way to stay consistent and save on every single order.
What if it doesn't work for me?
+Every order is backed by our 60-day money-back guarantee. Give it a fair try — most people notice a difference within two to four weeks as the strains establish themselves. If your gut isn't happier by then, simply reach out and we'll refund you: no complicated returns, no restocking fees, and no hard feelings.
Every formula is board-reviewed before it ships. Build your routine →
Rigorously tested. Reasonably priced.
Third-party tested
+We work with independent labs to test our products for purity, potency, and safety.
Formulated without compromise
+Our formulas are made without ingredients like artificial sweeteners, colors, or flavors, and without major allergens: gluten, soy, dairy, wheat, peanut, tree nut, eggs, fish, and shellfish, unless labeled otherwise.
Label accuracy
+We do extensive testing to guarantee our probiotic CFU counts through expiration, not just at the time of manufacture.
cGMP · Made in USA*
+Manufactured in cGMP-certified US facilities with globally sourced ingredients.
Stack your routine, save more.
Our top-selling bundles are designed with products that work better together. Save up to 15% when you subscribe.
Shop all bundles →
Gut Guardian Bundle
A complete daily routine designed to support digestive comfort and gut balance throughout the day, with proactive support against bloat and gas.
- 60B Probiotic
- Digestive Enzymes
- Bloat + Gas Probiotic
$75.97
/mo $79.97
Hack Your Tummy Bundle
Our bestselling bundle, designed to support overall digestive health and gut balance to help reduce bloating and feel your best throughout the day.
- 60B Probiotic
- Digestive Enzymes
$68.98
/mo $81.15
Gut Gummy Bundle
Delicious gummies that work to nourish your gut microbiome, promote regularity, and help you feel lighter and more balanced every day.
- Probiotic Gummies
- Fiber Gummies
$28.78
/mo $35.97Take a deeper dive into gut health
Fiber on Your GLP-1 Journey: Why It Matters and How to Get Enough
Marci Clow, MS, RDN
What Causes Bloating and What You Can Do About It
Marci Clow, MS, RDN
Using Probiotics for Bloating: Can They Help Your Microbiome?
Physician's Choice Team
Your gut's next chapter starts here.
Build your routine in less than two minutes, and start experiencing the benefits of a happier, healthier gut. ‡
Build your routineGet 15% off your first order
Join 250,000+ on a healthier gut.