Collagen Peptides Powder Collagen Peptides Powder

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Physician's Choice Grass Fed, Pasture Raised, Non-GMO, 100% Hydrolyzed Collagen Peptides Powder has been specially formulated with digestive enzymes for enhanced absorption and concentrated delivery of the beneficial amino acids collagen is known for. 

Our collagen is NOT your generic collagen that was thrown in a tub and put out on the shelf. Rather we worked with REAL medical doctors and formulators to develop a superior clean collagen product, that delivers the true benefits of collagen.

 

The Collagen Problem

We examined the bioavailability of collagen along with the research and studies behind what makes collagen effective. We ran tests, performed our own research and found no one was addressing the absorption issue associated with taking collagen supplements.

Collagen alone has a BIG absorption problem. Collagen, when taken without a bioavailability agent (like most collagen products on the market), isn't effectively absorbed into the bloodstream or intestinal wall, leaving large portions of the collagen sitting in your gut or excreted from the body. (Sometimes science is gross)

 

Our Solution 

We formulated a 100% pure twice hydrolyzed collagen peptides supplement with a natural occurring bioavailability agent to improve absorption.

By adding targeted digestive enzymes to break down the peptide chains we ensure that nearly all of the active tripeptides, dipeptides, and free amino acids are quickly released and absorbed. 

Without the science - We created a double hydrolyzed collagen peptides powder with digestive enzymes for enhanced absorption.

The digestive enzymes and double hydrolysis we use quickly breaks down the collagen peptides into the beneficial amino acids collagen is known for. Thus you get the true benefits of collagen without having to buy pounds of ineffective powder. 

The double hydrolysis of our collagen not only enhances absorption into your bloodstream, but it also easily mix with water, smoothies, or a cup of coffee

 

The Result

Our collagen is double hydrolized using an enzymatic process which completely breaks down the peptide chain. 

This double hydrolysis wasn't enough for us, we wanted more absorption from our collagen so we took it a step further and introduced a proven bioavailability agent.

By introducing targeted digestive enzymes including proteolytic enzymes (proteases) to break down the peptide chains into di-peptides, tripeptide, and amino acids.

Our collagen increases the pure concentration of beneficial amino acids that are effectively absorbed into the intestinal wall and bloodstream. These amino acids are what provide the many benefits we have all come to know collagen for.

Collagen Peptides Benefits : 

  • Improved Skin Elasticity (3)(4)

  • Supports Bones, Joints, and Ligaments (1)(2)

  • Aids in Reduction of Wrinkles and Facial Expression Lines (4)(9)

  • Supports Digestive Health (10)

  • Improved Body Composition (5)

  • Can Aid in Decrease of Cellulite (6)

 

How?

We partnered with legitimate certified medical doctors, a leading scientific enzyme lab, and world-renowned collagen supplier to create - 100% pure NON-GMO, Grass Fed, Hormone Free Hydrolyzed Collagen Peptides with DigSEB® a proven digestive enzyme blend. 

 

Our Partners - 

- SpecialityEnzymes a globally recognized manufacturer of enzymes and one of the worlds foremost enzymologists. Formulated DigSEB® a proven digestive enzyme blend with proteolytic enzymes (proteases) that break down the peptide chains.

 

-A world-renowned collagen supplier who produces clean label collagen recognized by the World Health Organization (WHO). Our collagen supplier provides the highest quality natural, non-allergenic, Non-GMO, grass fed, hormone free collagen we believe available.

Our collagen supplier invests in and practices sustainability throughout their entire production. From renewable energy and water conservation too their strict adherence to the Global Animal Partnership ensuring grass-fed pasture raised cattle.

- Our collagen product along with all our products is manufactured in the USA in an NSF®, cGMP certified facility.

Our suppliers like us focus on delivering one of the purest, products on the market.

 

What is Collagen?

Collagen on a basic level is the glue of the human body. It may sound like a rather simplistic definition, but it’s the truth. Collagen is literally the stuff that keeps us together! It can be found in our muscles, joints, nails, hair, and skin. Collagen is produced on a cellular level where it combines with special peptides and amino acids to create the kind of structural framework on which our entire body depends. 

Yes, the same collagen that helped hold together the bones of these lumbering big bovine beasts of the pasture has been condensed down into a powder-based hydrolyzed supplement! 

 

      Medicinal Facts:

      Collagen is the most important building block in the human body. Making up nearly 30% of the proteins in our body, Collagen is responsible for skin elasticity and regenerating connective tissues such as cartilage, ligaments, tendons, and bones. Collagen is created in our cells then combines with amino acids and peptides to provide structural tissue support.

       

       

      [4] Choi SY, Ko EJ, Lee YH, Kim BG, Shin HJ, Seo DB, Lee SJ, Kim BJ, Kim MN. Effects of collagen tripeptide supplement on skin properties: A prospective, randomized, controlled study. Journal of Cosmetic and Laser Therapy 16:3; 2014. p. 132-7.

         [7] Bello AE, Oesser S. Collagen Hydrolysate for the treatment of osteoarthritis and other joint disorders. Current Medical Research an Opinion 22; 2006. p. 2221-32.[1] Bello AE, Oesser S. Collagen Hydrolysate for the treatment of osteoarthritis and other joint disorders. Current Medical Research an Opinion 22; 2006. p. 2221-32.

        [8] Kim HK, Kim MG, Leem KH. Osteogenic Activity of Collagen Peptide via ERK/MAPK Pathway Mediated Boosting of Collagen Synthesis and Its Therapeutic Efficacy in Osteoporotic Bone by Back-Scattered Electron Imaging and Microarchitecture Analysis. Molecules, 18; 2013. p. 15474-89

        [9] Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser S. Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis. Skin Pharmacol Physiol 27; 2014. p. 113–119.

        Physician's Choice Grass Fed, Pasture Raised, Non-GMO, 100% Hydrolyzed Collagen Peptides Powder has been specially formulated with digestive enzymes for enhanced absorption and concentrated delivery of the beneficial amino acids collagen is known for. 

        Our collagen is NOT your generic collagen that was thrown in a tub and put out on the shelf. Rather we worked with REAL medical doctors and formulators to develop a superior clean collagen product, that delivers the true benefits of collagen.

         

        The Collagen Problem

        We examined the bioavailability of collagen along with the research and studies behind what makes collagen effective. We ran tests, performed our own research and found no one was addressing the absorption issue associated with taking collagen supplements.

        Collagen alone has a BIG absorption problem. Collagen, when taken without a bioavailability agent (like most collagen products on the market), isn't effectively absorbed into the bloodstream or intestinal wall, leaving large portions of the collagen sitting in your gut or excreted from the body. (Sometimes science is gross)

         

        Our Solution 

        We formulated a 100% pure twice hydrolyzed collagen peptides supplement with a natural occurring bioavailability agent to improve absorption.

        By adding targeted digestive enzymes to break down the peptide chains we ensure that nearly all of the active tripeptides, dipeptides, and free amino acids are quickly released and absorbed. 

        Without the science - We created a double hydrolyzed collagen peptides powder with digestive enzymes for enhanced absorption.

        The digestive enzymes and double hydrolysis we use quickly breaks down the collagen peptides into the beneficial amino acids collagen is known for. Thus you get the true benefits of collagen without having to buy pounds of ineffective powder. 

        The double hydrolysis of our collagen not only enhances absorption into your bloodstream, but it also easily mix with water, smoothies, or a cup of coffee

         

        The Result

        Our collagen is double hydrolized using an enzymatic process which completely breaks down the peptide chain. 

        This double hydrolysis wasn't enough for us, we wanted more absorption from our collagen so we took it a step further and introduced a proven bioavailability agent.

        By introducing targeted digestive enzymes including proteolytic enzymes (proteases) to break down the peptide chains into di-peptides, tripeptide, and amino acids.

        Our collagen increases the pure concentration of beneficial amino acids that are effectively absorbed into the intestinal wall and bloodstream. These amino acids are what provide the many benefits we have all come to know collagen for.

        Collagen Peptides Benefits : 

        • Improved Skin Elasticity (3)(4)

        • Supports Bones, Joints, and Ligaments (1)(2)

        • Aids in Reduction of Wrinkles and Facial Expression Lines (4)(9)

        • Supports Digestive Health (10)

        • Improved Body Composition (5)

        • Can Aid in Decrease of Cellulite (6)

         

        How?

        We partnered with legitimate certified medical doctors, a leading scientific enzyme lab, and world-renowned collagen supplier to create - 100% pure NON-GMO, Grass Fed, Hormone Free Hydrolyzed Collagen Peptides with DigSEB® a proven digestive enzyme blend. 

         

        Our Partners - 

        - SpecialityEnzymes a globally recognized manufacturer of enzymes and one of the worlds foremost enzymologists. Formulated DigSEB® a proven digestive enzyme blend with proteolytic enzymes (proteases) that break down the peptide chains.

         

        -A world-renowned collagen supplier who produces clean label collagen recognized by the World Health Organization (WHO). Our collagen supplier provides the highest quality natural, non-allergenic, Non-GMO, grass fed, hormone free collagen we believe available.

        Our collagen supplier invests in and practices sustainability throughout their entire production. From renewable energy and water conservation too their strict adherence to the Global Animal Partnership ensuring grass-fed pasture raised cattle.

        - Our collagen product along with all our products is manufactured in the USA in an NSF®, cGMP certified facility.

        Our suppliers like us focus on delivering one of the purest, products on the market.

         

        What is Collagen?

        Collagen on a basic level is the glue of the human body. It may sound like a rather simplistic definition, but it’s the truth. Collagen is literally the stuff that keeps us together! It can be found in our muscles, joints, nails, hair, and skin. Collagen is produced on a cellular level where it combines with special peptides and amino acids to create the kind of structural framework on which our entire body depends. 

        Yes, the same collagen that helped hold together the bones of these lumbering big bovine beasts of the pasture has been condensed down into a powder-based hydrolyzed supplement! 

         

            Medicinal Facts:

            Collagen is the most important building block in the human body. Making up nearly 30% of the proteins in our body, Collagen is responsible for skin elasticity and regenerating connective tissues such as cartilage, ligaments, tendons, and bones. Collagen is created in our cells then combines with amino acids and peptides to provide structural tissue support.

             

             

            [4] Choi SY, Ko EJ, Lee YH, Kim BG, Shin HJ, Seo DB, Lee SJ, Kim BJ, Kim MN. Effects of collagen tripeptide supplement on skin properties: A prospective, randomized, controlled study. Journal of Cosmetic and Laser Therapy 16:3; 2014. p. 132-7.

               [7] Bello AE, Oesser S. Collagen Hydrolysate for the treatment of osteoarthritis and other joint disorders. Current Medical Research an Opinion 22; 2006. p. 2221-32.[1] Bello AE, Oesser S. Collagen Hydrolysate for the treatment of osteoarthritis and other joint disorders. Current Medical Research an Opinion 22; 2006. p. 2221-32.

              [8] Kim HK, Kim MG, Leem KH. Osteogenic Activity of Collagen Peptide via ERK/MAPK Pathway Mediated Boosting of Collagen Synthesis and Its Therapeutic Efficacy in Osteoporotic Bone by Back-Scattered Electron Imaging and Microarchitecture Analysis. Molecules, 18; 2013. p. 15474-89

              [9] Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser S. Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis. Skin Pharmacol Physiol 27; 2014. p. 113–119.

              Product Details:

              • HIGH POTENCY; 7000mg of Collagen Hydolyzed Bovine, the highest potency available on the market; 30 servings / (7g/0.25 ounce).
              • ENHANCED ABSORPTION - 5X MORE EFFECTIVE; DigeSEB enzyme blend for Enhanced Absorption makes collagen 5x more effective.
              • BONES, SKIN, ANTI-AGING; Physician's Choice Collagen Peptides is an all-natural supplement to promote health of bones, skin, and reduce aging.
              • GAIN MUSCLE, LOSE FAT; Our natural Collagen Peptides helps improve body composition and prouduce less wavey skin.
              • PALEO APPROVED + HORMONE FREE
              • Manufacturing & Sourcing:

                Physician’s Choice Collagen Peptides is always the highest quality available, developed by the largest and most trusted SNF-GMP certified manufacturer of herbal extracts in the USA.

                Ingredients are acquired through industry best practices. This includes sustainable and socially conscious sourcing, implementation of stringent testing methods that include DNA, HPTLC and HPLC throughout processing and preparation of finished product.

                All ingredients sourced must pass multi-step quality control processing conducted by qualified scientists and technicians using advanced techniques to assure transparency, purity, and safety.

                Each stage of product journey is documented and verified from harvesting to packaging, guaranteeing the safest, most effective product possible.

              What Makes Our Collagen So Much Better?

              Collagen that is extracted from bovine bone is the most abundant source, and the collagen peptides that are isolated from this source typically consist of oligopeptides that are approximately <1000 Daltons (DA) [3]. It has been reported that peptide chains of this size are more bioactive than regular collagen molecules and polypeptides [3-5]. Di- and tripeptides are even more easily absorbed than oligopeptides [3-5]; therefore, Physician’s Choice has added a digestive enzyme blend (DigSEB) to their Collagen Peptides Powder to break down the oligopeptides even further.

              As a result, the hydrolyzed collagen in Physician’s Choice Collagen Powder is more effective than that in other supplements due to increased bioavailability of digestible peptides that are an optimal size (oligopeptides), and digestive enzymes including proteolytic enzymes (proteases) that break down the peptide chains into di- and tripeptides as well as amino acids. Research demonstrates that enzymes promote the thorough break down of peptides in collagen hydrolysate [6], thereby increasing the concentration of amino acids that reach the intestinal wall and the bloodstream. More specifically, studies show that the enzymatic hydrolysis (break down) of collagen peptides releases biologically active peptides that have potent antioxidant and antimicrobial properties that target joint problems and enhance overall health [7]. These findings are specific to hydrolyzed collagen, not regular collagen or gelatin [7, 8].

              One particular study compared the percentage of enzymatic hydrolysis of several forms of collagen that were exposed to different digestive enzymes for 120 minutes [6]. The samples included: crude collagen, powdered collagen, gelatin, and two types of collagen hydrolysates. The results showed that after 120 minutes there was only a little over 30% hydrolysis of the crude collagen. This indicates that large portions of the crude collagen remain un-hydrolyzed and are not absorbed by the body. 

              For the powdered collagen fiber and gelatin, there was an average of about 7% hydrolysis in the same time frame. It is argued that the high temperatures and grinding that is required to make the powdered form breaks peptide bonds and disorganizes the protein structure, thereby disrupting enzymatic hydrolysis [8-10]. Similarly, gelatin is typically obtained through acid of alkaline hydrolysis and this process can damage proteins [6, 7].

              Interestingly, the result of the comparative study showed that the hydrolyzed collagen samples had the lowest percentage of enzymatic hydrolysis (1-3%) in 120 minutes.  This actually reflects the fact that hydrolyzed collagen is already comprised of almost completely hydrolyzed peptides bonds [6]. Furthermore, the enzymatic hydrolysis process that produces hydrolyzed collagen does not destroy its proteins [6]. This means that exposing hydrolyzed collagen to digestive enzymes ensures that nearly all of the biologically active tripeptides, dipeptides, and free amino acids are quickly released and absorbed into the intestinal wall, whereas portions of regular collagen or gelatin that are un-hydrolyzed in 120 minutes or less will be excreted from the body. 

              The blend of both type I and type III collagen in Physician’s Choice Collagen Peptides makes it more effective than supplements that only contain one form, as type I collagen promotes hair, skin, and nail health, and the combination of type I and III supports muscle tissue health [1, 2]. In addition, hydrolyzed collagen is in the form of peptide chains that are much easier to digest and absorb than supplements that are comprised of regular collagen or gelatin [3]. The molecules that comprise regular collagen are too large to be absorbed by the intestines. This causes stomach enzymes to impartially break down regular collagen, which results in only a small amount being released into the intestinal tract and the rest is simply excreted from the body.

              Therefore, the digestive enzyme blend in this supplement quickly and efficiently releases the 14 essential amino acids in the Type I and Type III Hydrolyzed Collagen, thereby promoting healthy skin, hair and nails, along with healthy joints, ligaments, and tendons. These factors make it more effective than regular collagen.

               

              References

              1. Asserin J, Lati E, Shioya T, Prawitt J. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. J Cosmet Dermatol. 2015;14(4):291-301.
              2. de Moraes LO, Lodi FR, Gomes TS, et al. Immunohistochemical expression of types I and III collagen antibodies in the temporomandibular joint disc of human foetuses. Eur J Histochem. 2011;55(3):e24.
              3. Song H, Zhang S, Zhang L, Li B. Effect of Orally Administered Collagen Peptides from Bovine Bone on Skin Aging in Chronologically Aged Mice. Nutrients. 2017;9(11).
              4. Bouglé D., Bouhallab S. Dietary bioactive peptides: Human studies. Crit. Rev. Food Sci. Nutr. 2017;57:335-343.
              5. Jia J., Zhou Y., Lu J., Chen A., Li Y., Zheng G. Enzymatic hydrolysis of Alaska pollack (Theragra chalcogramma) skin and antioxidant activity of the resulting hydrolysate. J. Sci. Food Agric. 2010;90:635-640.
              6. IItchenco S, Kempka AP, Prestes RC. Profiles of enzymatic hydrolysis of different collagens and derivatives over time. R. bras. Tecnol. Agroindustr. 2017; 11(1): 2165-2185.
              7. Gomes-Guillen MC, et al. Functional and bioactive properties of collagen and gelatin from alternative sources: A review. Food Hydrocolloids. 2011;25(8):1813-1827.
              8. Schrieber R, Gareis H. Gelatine handbook: theory and industrial practice. Wiley-VCH Verlag GmbH & Co. KGaA: Weinheim, 334 p., 2007.
              9. Pereira AGT, et al. Effects of the addition of mechanically deboned poultry meat and collagen fibers on quality characteristics of frankfurter-type sausages. Meat Science. 2011;89: 519-525.
              10. Wolf KL, et al. Physicochemical characterization of collagen fibers and collagen powder for self-composite film production. Food Hydrocolloids. 2009;23(7):1886-1894.

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