Physician's Choice
Physician's Choice Vaginal Probiotic Strains: GR-1™, RC-14™ and LBV88™
Physician's Choice Vaginal Probiotic has 6 billion CFU from three strains: Lacticaseibacillus rhamnosus GR-1™, Limosilactobacillus reuteri RC-14™ and Lactobacillus crispatus LBV88™. A serving is 1 capsule, there are 30 in a bottle, and the label prints one count for the whole 70 mg blend, not an amount for each strain. GR-1™ and RC-14™ were tested together in a 2003 trial; LBV88™ was not.
By the Physician's Choice Team. Updated October 13, 2026. Product facts are from our Supplement Facts panels, product pages and strain records.
What the Vaginal Probiotic label lists
This is one capsule, as the Supplement Facts panel on our Vaginal Probiotic page prints it:
- Organic acacia fiber: 150 mg
- Organic cranberry (fruit) extract: 75 mg
- Vaginal Probiotic Blend: 70 mg, with a total probiotic activity of 6 billion CFU from Limosilactobacillus reuteri RC-14™, Lactobacillus crispatus LBV88™ and Lacticaseibacillus rhamnosus GR-1™
- Deglycyrrhizinated licorice root extract (DGL): 50 mg
- Other ingredients: vegetable capsule (hypromellose, gellan gum), rice flour, rice hull concentrate, gum arabic and sunflower oil
The serving size is 1 capsule, with 30 servings per container. Our product page also describes the formula as vegan, gluten-free and dairy-free. How we test every lot of our products is explained on our third-party testing page.
Why the code after each name matters
The NIH Office of Dietary Supplements (ODS) explains that probiotics are named by their genus, species and strain. Its example is Lacticaseibacillus rhamnosus GG: Lacticaseibacillus is the genus, rhamnosus is the species and GG is the strain. GR-1™ is a different strain of that same species.
ODS also says that any health benefit a probiotic has depends on the specific strains it contains as well as its CFU count. That makes the strain code the detail to match when you read about a probiotic. ODS points shoppers to the product label for the genus, species and strain of each microorganism, and our label prints a code after every species in the blend.
Our label also notes that LBV88™, GR-1™ and RC-14™ are trademarks of Chr. Hansen A/S.
The three strains and the trial we cite
Each row is one strain as our label prints it, what its code points to, and the one published human trial this page cites.
| Strain on the label | What the code identifies | The published human trial we cite |
|---|---|---|
| Lacticaseibacillus rhamnosus GR-1™ | One strain of the species L. rhamnosus, not the species as a whole | Reid and colleagues, 2003. Randomized and placebo-controlled. 64 healthy women. Taken by mouth every day for 60 days, together with RC-14™. Researchers measured vaginal flora. |
| Limosilactobacillus reuteri RC-14™ | One strain of the species L. reuteri. The 2003 paper calls it L. fermentum RC-14™, with the same code. | The same 2003 trial, taken together with GR-1™ |
| Lactobacillus crispatus LBV88™ | One strain of the species L. crispatus | Not part of the 2003 trial |
No amount is printed for any single strain, only the 6 billion CFU total for the blend.
What the 2003 trial did and did not test
GR-1™ and RC-14™ were studied together in a 2003 randomized, placebo-controlled trial in which 64 healthy women took them by mouth for 60 days and researchers measured vaginal flora (Reid and colleagues; RC-14™ was then named L. fermentum RC-14™).
That design sets the limits of what the trial can tell you. It gave the two strains together, so it says nothing about either strain on its own. It did not include LBV88™. It used its own capsules of GR-1™ and RC-14™, not Vaginal Probiotic, which adds a third strain, organic acacia fiber, organic cranberry extract and DGL licorice root extract. Our label does not show how much GR-1™ or RC-14™ each capsule holds, so this page does not compare the trial’s capsules with ours.
We cite the trial for its design and for what it measured: vaginal flora. The full abstract is on PubMed.
Vaginal Probiotic or Women's Probiotic: which is which
Our Women's Probiotic is a separate formula, and its label shares no species and no strain with Vaginal Probiotic.
- Vaginal Probiotic. 3 strains, each printed with its code, at 6 billion CFU in a 70 mg blend. The capsule also holds organic acacia fiber (150 mg), organic cranberry (fruit) extract (75 mg) and DGL licorice root extract (50 mg). 1 capsule a day.
- Women's Probiotic. 50 billion CFU in a 133 mg blend of 6 species. Its label prints the species names only; our strain records give the codes: Lactiplantibacillus plantarum Lp-115®, Lacticaseibacillus paracasei Lpc-37®, Lacticaseibacillus casei Lc-11®, Lactobacillus gasseri Lg-36™, Lactobacillus acidophilus La-14® and Bifidobacterium lactis Bl-04®. The capsule also holds a 100 mg prebiotic blend (organic inulin from Jerusalem artichoke, organic acacia fiber), D-mannose (60 mg) and cranberry fruit powder (50 mg). 1 capsule a day.
If you are looking for Lactobacillus crispatus, GR-1™ or RC-14™, Vaginal Probiotic is the one of the two that lists them. The two CFU counts are not a ranking: ODS notes that a product with more CFUs does not necessarily offer greater health benefits for that reason alone.
How to take Vaginal Probiotic
Take 1 capsule a day with a full glass of water, morning or night. Our product page says you can take it with or without food, and suggests the same time each day. A bottle holds 30 capsules.
What a probiotic cannot do
Vaginal Probiotic is a dietary supplement formulated to support vaginal health and is not intended to diagnose, treat, cure, or prevent any disease.
The trial on this page tested two of its strains, not Vaginal Probiotic itself, so it is not a study of this product. What the FDA does and does not do for supplements is set out on our page Is Physician's Choice FDA approved? Our side effects page covers who should check with a doctor before taking a probiotic.
Questions shoppers ask
Is Vaginal Probiotic formulated for vaginal pH?
Vaginal Probiotic is formulated to help balance vaginal pH‡
Can I take Vaginal Probiotic while pregnant or breastfeeding?
If you are pregnant or breastfeeding, talk to your doctor before taking Vaginal Probiotic.
Can I take it with Women's Probiotic, or instead of it?
They are different formulas, and their labels share no species and no strain: GR-1™, RC-14™ and LBV88™ are on Vaginal Probiotic only. Each is 1 capsule a day. Our Women's Probiotic page says the two can be taken together, and asks you to check with your doctor before starting any new supplement routine.
How do I take Vaginal Probiotic?
Take 1 capsule a day with a full glass of water, morning or night, with or without food. Our product page suggests taking it at the same time each day.
Why does the label say crispatus LBV88™ and not just crispatus?
Because a probiotic is named by its genus, species and strain, as the NIH Office of Dietary Supplements explains. LBV88™ is the strain code, so it tells you which Lactobacillus crispatus is in the capsule. Our Women's Probiotic label does not list L. crispatus.
Is Vaginal Probiotic vegan and gluten-free?
Our product page describes it as vegan, gluten-free and dairy-free. If you have known allergies, review the product’s ingredient list and allergen information and consult your healthcare provider before purchasing or using it. Most of our products are formulated without the top 9 common allergens, but ingredients vary by product.
‡These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Sources: Probiotics: Fact Sheet for Consumers, from the NIH Office of Dietary Supplements (updated November 17, 2025); Reid G and colleagues, randomized, placebo-controlled trial in 64 healthy women, 2003 (PubMed 12628548). Product facts: our Supplement Facts panels, product pages and strain records.