Best Probiotic for Bloating and Gas? Choose a Strain Studied for Bloating
Written by: Physician's Choice Team
Reviewed by: Hayley Miller, MS, RDN, LD
Updated Oct 28, 2026 · 11 sources
Choose a probiotic strain studied for bloating, at the daily amount the study used. Physician’s Choice Bloat + Gas Probiotic lists Bacillus subtilis OPTIBIOME BS50™ at 2 billion CFUs, the strain and daily amount from a 6-week placebo-controlled trial in healthy adults.1,2 For occasional bloating, a well-studied probiotic may help.‡ If bloating is persistent, severe, or feels different than usual, talk with your healthcare provider.
Key Takeaways:
- Probiotic effects can be specific to the strain, so the NIH Office of Dietary Supplements (ODS) says recommendations need to be strain-specific.3
- In a 6-week trial of 76 healthy adults, more people improved on a combined bloating, burping and flatulence score with BS50™ at 2 billion CFU a day than with a placebo (47.4% vs 22.2%).2
- Physician’s Choice Bloat + Gas Probiotic lists Bacillus subtilis OPTIBIOME BS50™ at 2 billion CFUs per capsule, with lactase, alpha-galactosidase and tributyrin.1
Why does the strain matter most for bloating?
Because a probiotic result belongs to the strain that produced it. ODS names a probiotic by genus, species and an alphanumeric strain designation, and says clinical recommendations need to be strain-specific because effects can be specific to certain strains.3 NCCIH adds that what one kind of Lactobacillus does, another kind, or any Bifidobacterium, will not necessarily do.4
So start with the study behind the strain: who took part, what daily amount and for how long. ODS reports that the World Gastroenterology Organization recommends clinicians advise only strains, doses and durations shown to be beneficial in human studies.3 A 2014 overview makes the same point: probiotic properties have been shown to be strain specific, so identifying the exact strain is very important.5 The count comes second: ODS says many supplements carry 1 to 10 billion CFU per dose, and higher counts are not necessarily more effective.3
What did the BS50™ trial find for bloating?
More people improved on a combined bloating, burping and flatulence score than with a placebo. In a randomized, double-blind, placebo-controlled trial published in 2022, 76 healthy adults took Bacillus subtilis BS50™ at 2 billion CFU a day, or a placebo, for 6 weeks. Of the BS50™ group, 47.4% improved on that score, compared with 22.2% of the placebo group.2
That is the strain and the daily amount printed on Physician’s Choice Bloat + Gas Probiotic: Bacillus subtilis OPTIBIOME BS50™, 2 billion CFUs per capsule, one capsule a day.1
| What to check | What the BS50™ trial reported | Why it matters when you choose |
|---|---|---|
| The strain | Bacillus subtilis BS50™.2 | Look for this code on the label. |
| Who took part | 76 healthy adults aged 30 to 65 with no significant digestive condition, who reported at least some bloating, burping or flatulence in the week before the first dose.2 | Results speak to people like these. |
| Daily amount and length | One capsule of 2 billion CFU a day for 6 weeks, with symptoms compared at week 6.2 | Match the label amount; give it 6 weeks. |
| Main result | 47.4% of the BS50™ group improved on one combined score for bloating, burping and flatulence together, compared with 22.2% of the placebo group.2 | The trial’s main measure. |
When should you see a doctor about bloating?
When it is intense, lasting or new for you. If bloating is persistent, severe, or feels different than usual, talk with your healthcare provider. For occasional bloating, a well-studied probiotic may help.‡
For occasional gas and bloating after meals, choose a digestive enzyme that helps break down the food components that may be causing discomfort: lactase for lactose in dairy, or alpha-galactosidase for certain carbohydrates in foods like beans, lentils, broccoli, and cabbage.‡ Bloat + Gas Probiotic puts the probiotic and the enzymes in one capsule: BS50™ at 2 billion CFUs, plus lactase and alpha-galactosidase in a 36 mg enzyme blend.1
How long should I take probiotics for bloating?
At least as long as the study behind your strain ran. The BS50™ trial gave one 2 billion CFU dose a day for 6 weeks and compared symptoms at week 6.2 ODS suggests asking your healthcare provider which probiotic to choose, what dose to take and how long to use it.6
Before you start, note how often bloating shows up in a normal week, as the trial did for a week before the first dose, then compare at week 6.2 The effects of probiotics may vary from person to person, NCCIH notes.7 At one capsule a day, a 30-capsule bottle of Bloat + Gas Probiotic lasts 30 days, so matching the 6-week trial takes two bottles.1
Probiotics help support digestive comfort by addressing bloating, burping, and occasional gas; enzymes help break down carbohydrates and dairy; and a postbiotic helps support a healthy gut lining.‡
The Bloat + Gas Probiotic label, entry by entry
Here is the Supplement Facts panel line by line, with what each ingredient is. The label gives three blends as total milligrams, so the table shows each blend amount as printed.1
| Label line, as printed | Amount per capsule | What it is (source) |
|---|---|---|
| Tributyrin (as CoreBiome®) | In the 325 mg Pre, Pro, Post-biotic Blend | A triglyceride made of glycerol and three butyric acid units, according to the NIH’s PubChem database.8 |
| Bacillus subtilis OPTIBIOME BS50™ | 2 billion CFUs, in the same blend | A probiotic bacterium, and the strain tested in the 6-week trial above at the same 2 billion CFU daily amount.1,2 |
| Organic Acacia Fiber | In the same blend | Acacia (gum arabic) is on FDA’s list of non-digestible carbohydrates it intends to propose adding to its dietary fiber definition.9 |
| Herbal Blend: Artichoke Leaf, Ginger Root | 50 mg | Two plant ingredients, named on the label as artichoke leaf and ginger root.1 |
| Enzyme Blend: Lactase, Alpha-galactosidase | 36 mg | Lactase breaks down lactose, the sugar in milk and dairy foods. Alpha-galactosidase can help break down galactooligosaccharides, found mostly in beans, root vegetables and some dairy products, Johns Hopkins Medicine says.10 |
| Other ingredients | Listed by name | Vegetable capsule (hypromellose, gellan gum), rice flour, medium chain triglycerides, silicon dioxide, rice hulls, rice extract, gum arabic, and sunflower oil.1 |
| Serving | 1 capsule; 30 servings per bottle | The product page direction: Take one (1) capsule daily.1 |
Our products are developed with our Scientific Advisory Board, which meets quarterly to discuss, review and approve our formulations. Every lot of every product is tested for purity and potency at ISO/IEC 17025-accredited labs, the international standard for testing-lab competence. See the label.
Physician’s Choice Digestive Enzymes also lists Bacillus subtilis OPTIBIOME BS50™, in its 159 mg prebiotic and probiotic blend with Bacillus coagulans and Bacillus clausii.11 Bloat + Gas Probiotic is the one whose label prints BS50™ at 2 billion CFUs, the trial’s daily amount.1
Gas after one food, or a daily routine?
Each has its own page. Gas after one food: our enzyme-by-food guide. Probiotic, enzymes or both: Probiotic or Digestive Enzymes. Our 60 Billion Probiotic and Digestive Enzymes routine: Probiotics for Bloating. Common causes: Why Am I So Bloated? A label checklist: What Is the Best Probiotic to Take?
Who should check with a healthcare provider first
If you are pregnant or breastfeeding, are seriously ill, or have a weakened immune system, consult your healthcare provider before taking a probiotic or any other dietary supplement.
Our Kids line includes a Kids Chewable Probiotic, Fiber Gummies, and a Probiotic + Fiber Powder. These are the only Physician’s Choice products we recommend for children under 18, and each should be used according to its labeled age range and directions. Always consult your child’s pediatrician or healthcare provider before starting a new supplement routine.
If you have known allergies, review the product’s ingredient list and allergen information and consult your healthcare provider before purchasing or using it. Most of our products are formulated without the top 9 common allergens, but ingredients vary by product.
Frequently Asked Questions
What is the best probiotic for bloating and gas?
Choose one whose strain has been studied for bloating, at the daily amount the study used. Physician’s Choice Bloat + Gas Probiotic lists Bacillus subtilis OPTIBIOME BS50™ at 2 billion CFUs, the strain and daily amount from a 6-week trial in healthy adults where more people improved on a combined bloating, burping and flatulence score with it than with a placebo (47.4% vs 22.2%).
How long should I take probiotics for bloating?
Give it at least as long as the study behind the strain ran. The BS50™ trial gave one 2 billion CFU dose a day for 6 weeks and compared symptoms at week 6.
Does the strain matter more than the CFU count?
Yes. The NIH Office of Dietary Supplements says probiotic effects can be specific to the strain, so recommendations need to be strain-specific. Look for the strain code on the label, then the study behind it, and match the daily amount that study used.
How do I know if probiotics are working for bloating?
Note how often bloating shows up in the week before you start, then compare at week 6. NCCIH notes that the effects of probiotics may vary from person to person.
The Bottom Line
Choose the strain first: one studied for bloating, at the amount and length the study used. Physician’s Choice Bloat + Gas Probiotic lists Bacillus subtilis OPTIBIOME BS50™ at 2 billion CFUs, the strain and daily amount from a 6-week placebo-controlled trial. For occasional bloating, a well-studied probiotic may help.‡ If bloating is persistent, severe, or feels different than usual, talk with your healthcare provider.
‡These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Sources
- Physician’s Choice. Bloat + Gas Probiotic product page and Supplement Facts label (version 3.1.0).
- Garvey SM, Mah E, Blonquist TM, Kaden VN, Spears JL. The probiotic Bacillus subtilis BS50 decreases gastrointestinal symptoms in healthy adults: a randomized, double-blind, placebo-controlled trial. Gut Microbes. 2022 Jan-Dec;14(1).
- NIH Office of Dietary Supplements (ODS). Probiotics: Fact Sheet for Health Professionals. Updated March 25, 2025.
- National Center for Complementary and Integrative Health (NCCIH). Probiotics: Usefulness and Safety. Last updated August 2019.
- Fijan S. Microorganisms with Claimed Probiotic Properties: An Overview of Recent Literature. Int J Environ Res Public Health. 2014;11(5):4745-4767.
- ODS. Probiotics: Fact Sheet for Consumers. Updated November 17, 2025.
- NCCIH. 5 Things To Know About Probiotics.
- PubChem, National Library of Medicine. Tributyrin (CID 6050).
- U.S. Food and Drug Administration (FDA). Questions and Answers on Dietary Fiber. Content current as of July 25, 2024.
- Johns Hopkins Medicine. Digestive Enzymes and Digestive Enzyme Supplements.
- Physician’s Choice. Digestive Enzymes product page and Supplement Facts label (version 3.7.0).
How this page was made
Sources fetched October 22 and 27, 2026. Label facts: our Bloat + Gas Probiotic (version 3.1.0) and Digestive Enzymes (version 3.7.0) Supplement Facts labels and product pages. Written by Physician’s Choice.
