Digestive Enzymes | Physician's Choice

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Physician's Choice Digestive Enzymes bottle and box, 60 capsules, with prebiotics and probiotics, 16 enzymes
Hand reaching for a Digestive Enzymes bottle on a pink picnic blanket beside crackers and dried fruit
Hand holding one Digestive Enzymes capsule beside four labeled benefit tags on a dark red background
Digestive Enzymes capsule beside three numbered points: 16 digestive enzymes, 3 probiotic strains, 150mg botanical blend
Digestive Enzymes and 60 Billion Probiotic boxes on a dark red background with two callout labels
Digestive Enzymes Supplement Facts label for the 60 capsule bottle
Physician's Choice Digestive Enzymes bottle and box, 90 capsules, with prebiotics and probiotics, 16 enzymes
Physician's Choice Digestive Enzymes bottle and box, 180 capsules, with prebiotics and probiotics, 16 enzymes
Physician's Choice Digestive Enzymes bottle and box, 60 capsules, with prebiotics and probiotics, 16 enzymes
Hand reaching for a Digestive Enzymes bottle on a pink picnic blanket beside crackers and dried fruit
Hand holding one Digestive Enzymes capsule beside four labeled benefit tags on a dark red background
Digestive Enzymes capsule beside three numbered points: 16 digestive enzymes, 3 probiotic strains, 150mg botanical blend
Digestive Enzymes and 60 Billion Probiotic boxes on a dark red background with two callout labels
Digestive Enzymes Supplement Facts label for the 60 capsule bottle
Physician's Choice Digestive Enzymes bottle and box, 90 capsules, with prebiotics and probiotics, 16 enzymes
Physician's Choice Digestive Enzymes bottle and box, 180 capsules, with prebiotics and probiotics, 16 enzymes
view nutrient label

Verified Customer Reviews

Digestive Enzymes
Digestive Enzymes
Verified Buyer
Finally Found Something That Works

“I’ve always had trouble with bloating and breaking down my food. I saw this all over TikTok, and I decided to order it, and I was not disappointed. If you’re having trouble with breaking down your food and belly bloat, I highly suggest these.

”Tammy Hardenburg.
Digestive Enzymes

  4.5 Less than 1% ask for a refund

Digestive Enzymes

A fast-acting 3-in-1 blend of 16 enzymes, 3 probiotic strains, and prebiotic fiber, built to break down food, beat the bloat, and make every meal a happy one.

A fast-acting 3-in-1 blend of 16 enzymes, 3 probiotic strains, and prebiotic fiber, built to break down food, beat the bloat, and make every meal a happy one.

Physician's Choice
Supports Digestive Health‡
Physician's Choice
Helps Reduce Bloating‡
Physician's Choice
Promotes Nutrient Absorption‡
Physician's Choice
Supports Gut Function‡
  • 16 enzymes break down proteins, fats, dairy, and carbs‡
  • Eases mealtime bloating and discomfort‡
  • Promotes better nutrient absorption‡
  • 3-in-1: enzymes + probiotics + prebiotics‡
  • Built for heavy meals and sensitive stomachs

Best results seen after a few months of consistent use

Size
Digestive Enzymes

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Who is this product for?

Digestive Enzymes is designed for anyone who feels weighed down after meals, whether that’s bloating, gas, sluggishness, or general discomfort. It’s especially helpful if you:

  • Often feel bloated or heavy after eating
  • Struggle with rich, fatty, or protein-heavy meals
  • Follow a plant-based, keto, or high-fiber diet
  • Notice your digestion has slowed down with age
  • Want to get more out of the food you already eat

Our Kids line includes a Kids Chewable Probiotic, Fiber Gummies, and a Probiotic + Fiber Powder. These are the only Physician’s Choice products we recommend for children under 18, and each should be used according to its labeled age range and directions. Always consult your child’s pediatrician or healthcare provider before starting a new supplement routine.

If you are pregnant or breastfeeding, are seriously ill, or have a weakened immune system, consult your healthcare provider before taking a probiotic or any other dietary supplement.

Why do I need Digestive Enzymes?

Your body naturally produces enzymes to break down the food you eat.

Proteases for protein, lipases for fat, amylases for carbs, and so on.

But several things can leave your natural enzyme production short of what your meals demand, including aging, stress, processed diets, and certain food sensitivities.

When enzyme activity falls behind, food sits in the gut longer than it should. That’s when you feel the bloating, gas, fullness, and discomfort that turn meals into something you regret instead of enjoy.

Our formula goes a step further than enzymes alone. It pairs 16 targeted digestive enzymes with prebiotic fibers and probiotic strains to nourish a healthy gut, plus organic peppermint and ginger to soothe the stomach, giving your digestion full-spectrum suppo

Benefits

  • Helps reduce occasional bloating so you feel lighter after meals
  • Eases post-meal discomfort and that heavy, sluggish feeling
  • Supports better digestion of proteins, fats, and carbohydrates
  • Improves nutrient absorption so your body gets more from your food
  • Nourishes a healthy gut microbiome with prebiotic fibers and probiotic strains
  • Soothes the stomach with organic peppermint and ginger
  • Doctor-developed formula combining 16 targeted digestive enzymes

Manufacturing Claims

Every bottle of Physician’s Choice Digestive Enzymes is manufactured to high standards you can trust:

  • Made in the USA in a cGMP-certified facility
  • Third-party tested for purity and potency
  • Non-GMO
  • Vegan and vegetarian-friendly capsules
  • Dairy-free, soy-free
  • No artificial fillers, binders, or preservatives
  • Formulated with input from medical professionals

Recommended Usage

Take 1 capsule with your largest meal of the day, or as directed by your healthcare provider. For best results, take consistently. Most people start noticing a difference within the first week.

Store in a cool, dry place away from direct sunlight. Keep out of reach of children. Do not use if the safety seal is broken or missing.

Supplement Facts & Ingredients

Serving Size: 1 Capsule · Servings Per Container: 60

Prebiotic and Probiotic Blend, 159 mg
:
 
Organic Inulin (from Jerusalem Artichoke), Organic Acacia Fiber, Inulin (from Chicory), Bacillus subtilis OPTIBIOME BS50™, Bacillus coagulans, Bacillus clausii

Herbal Blend, 150 mg:
Peppermint Leaf, Ginger Root

Digestive Enzyme Blend, 85 mg: 
Bromelain, Amylase, Protease 4.5, Glucoamylase, Protease 6.0, Papain, Lactase, Protease 3.0, Peptidase, Cellulase, Beta-Glucanase, Alpha-Galactosidase, Lipase, Xylanase, Hemicellulase, Invertase† Daily Value (DV) not established.

Other ingredients:
Vegetable capsule (hypromellose), rice flour, rice hull concentrate, gum arabic, and sunflower oil.OPTIBIOME BS50™ is a trademark of BIO-CAT, Inc.

view nutrient label

Verified Customer Reviews

Digestive Enzymes
Digestive Enzymes
Verified Buyer
Finally Found Something That Works

“I’ve always had trouble with bloating and breaking down my food. I saw this all over TikTok, and I decided to order it, and I was not disappointed. If you’re having trouble with breaking down your food and belly bloat, I highly suggest these.

”Tammy Hardenburg.
Digestive Enzymes
View nutrient label
Verified customer reviews
Finally found something that works
Verified buyer

"I've always had trouble with bloating and breaking down my food. I saw this all over TikTok and decided to order it, and I was not disappointed. If you're having trouble with breaking down your food and belly bloat, I highly suggest these."

— Tammy Hardenburg
4.5 Less than 1% ask for a refund

Digestive Enzymes

A fast-acting 3-in-1 blend of 16 enzymes, 3 probiotic strains and prebiotic fiber, built to break down food, beat the bloat, and make every meal a happy one.‡

Supports digestive health‡
Helps reduce bloating‡
Promotes nutrient absorption‡
Supports gut function‡
16 enzymes break down proteins, fats, dairy and carbs‡ Eases mealtime bloating and discomfort‡ Promotes better nutrient absorption‡ 3-in-1: enzymes + probiotics + prebiotics‡ Built for heavy meals and sensitive stomachs
Best results seen after a few months of consistent use
Select size
Free shipping always ($4.99 value) Easily edit, skip or cancel anytime Guaranteed delivery during sell-outs VIP access to exclusive drops
Add to cart $20.16
Easy 60-day returns — try it risk-free for 60 days
Customer favorite
Less than 1% return this product.
Your order is protected by
60-day money-back guarantee

If you don't love it — even on day 59 — full refund.

Real people, real talk

Anyone who feels weighed down after meals: bloating, gas, sluggishness or general discomfort. It's especially helpful if you often feel heavy after eating, struggle with rich or protein-heavy meals, follow a plant-based, keto or high-fiber diet, or have noticed digestion slowing with age. Our Kids line includes a Kids Chewable Probiotic, Fiber Gummies, and a Probiotic + Fiber Powder. These are the only Physician’s Choice products we recommend for children under 18, and each should be used according to its labeled age range and directions. Always consult your child’s pediatrician or healthcare provider before starting a new supplement routine. If you are pregnant or breastfeeding, are seriously ill, or have a weakened immune system, consult your healthcare provider before taking a probiotic or any other dietary supplement.

Your body makes its own enzymes to break food down — proteases for protein, lipases for fat, amylases for carbs. Aging, stress, processed diets and food sensitivities can leave that production short of what your meals demand. When enzyme activity falls behind, food sits in the gut longer than it should, and that is when the bloating and fullness show up. This formula pairs 16 targeted enzymes with prebiotic fiber, probiotic strains, and organic peppermint and ginger to soothe the stomach.

Helps reduce occasional bloating so you feel lighter after meals. Eases post-meal discomfort and that heavy, sluggish feeling. Supports better digestion of proteins, fats and carbohydrates. Improves nutrient absorption. Nourishes a healthy gut microbiome with prebiotic fibers and probiotic strains. Soothes the stomach with organic peppermint and ginger.‡

Made in the USA in a cGMP-certified facility. Third-party tested for purity and potency. Non-GMO. Vegan and vegetarian-friendly capsules. Dairy-free, soy-free. No artificial fillers, binders or preservatives.

Take 1 capsule with your largest meal of the day, or as directed by your healthcare provider. For best results, take consistently — most people start noticing a difference within the first week. Store in a cool, dry place away from direct sunlight.‡

Serving size 1 capsule. Prebiotic and probiotic blend 159mg: organic inulin (Jerusalem artichoke), organic acacia fiber, inulin (chicory), Bacillus subtilis OPTIBIOME BS50™, Bacillus coagulans, Bacillus clausii. Herbal blend 150mg: peppermint leaf, ginger root. Digestive enzyme blend 85mg: bromelain, amylase, protease 4.5, glucoamylase, protease 6.0, papain, lactase, protease 3.0, peptidase, cellulase, beta-glucanase, alpha-galactosidase, lipase, xylanase, hemicellulase, invertase.

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Full label as textSupplement Facts: Digestive Enzymes

As printed on the 60 count bottle label. The Digestive Enzyme Blend lists 16 enzymes.

Supplement Facts Serving Size 1 Capsule Servings Per Container 60
Amount Per Serving%DV
Prebiotic and Probiotic Blend159 mg†
Organic Inulin (from Jerusalem Artichoke), Organic Acacia Fiber, Inulin (from Chicory), Bacillus subtilis OPTIBIOME BS50™, Bacillus coagulans, Bacillus clausii
Herbal Blend150 mg†
Peppermint Leaf, Ginger Root
Digestive Enzyme Blend85 mg†
Bromelain, Amylase, Protease 4.5, Glucoamylase, Protease 6.0, Papain, Lactase, Protease 3.0, Peptidase, Cellulase, Beta-Glucanase, Alpha-Galactosidase, Lipase, Xylanase, Hemicellulase, Invertase
† Daily Value (DV) not established
Other ingredients
Vegetable capsule (hypromellose), rice flour, rice hull concentrate, gum arabic, and sunflower oil.
Formulated without
Dairy, Soy, Wheat, Peanuts, Tree Nuts, Sesame, Eggs, Fish, Shellfish, GMOs, Color Additives, Artificial Sweeteners, or Preservatives
Allergen statement
Manufactured in a facility that also processes dairy, soy, gluten, wheat, tree nuts, peanuts, eggs, fish, shellfish, and sesame.
Trademark
OPTIBIOME BS50™ is a trademark of BIO-CAT, Inc.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Recommended by specialists

Trust your gut to the experts

Gastroenterologists, naturopaths and nutritionists review the evidence behind every formula we make.

8 Physicians, NDs & PhDs
8 Specialties, gastro to OB/GYN
100% Of formulas reviewed
MD, PhD
In their words 1 / 8

“Children's guts aren't just small adult guts — every kids formula has to earn its place in the evidence.”

Anders Dahlstrom Dr. Anders Dahlstrom, MD, PhD — Pediatric gastroenterology

How it works once you start

The enzymes work at your very first meal. The gut side lands between day 5 and day 14.‡
Day 1
First meal

Enzymes meet your first meal

16 enzymes go to work in the stomach, where digestion actually starts — breaking down protein, fat, dairy, starch and fibrous veg before any of it can sit heavy or ferment into gas.‡

Days 2–4
Results begin

Meals stop sitting heavy

Less post-meal bloating and heaviness as food gets broken down instead of lingering. Organic peppermint and ginger settle the stomach while the enzymes do the work.‡

Days 5–14
Results

The gut side catches up

3 Bacillus spore strains survive stomach acid on their own and settle in, with prebiotic fiber feeding them. Digestion starts feeling smoother between meals, not just after them.‡

Week 3+
New baseline

Eat what you like again

Enzymes handling each meal, probiotics and prebiotics holding the balance between them. The foods you'd started avoiding stop being a decision.‡

One capsule with your biggest meal. That's the whole routine.

As featured in

Physician's Choice Digestive Enzymes make every meal easier on your gut, and the difference can be felt from the very first bite. Join thousands of happy customers who've made mealtime bloat a thing of the past.

Why choose Physician's Choice Digestive Enzymes

16 enzymes, 1 capsule

A diverse blend tackles proteins, fats, dairy, carbs and veggies so no food is off the table.‡

Beat the mealtime bloat

Eases post-meal discomfort, heaviness and gas so you can eat what you love without the regret.‡

3-in-1 gut support

Enzymes, 3 probiotic strains and prebiotic fiber team up to support gut function and digestive wellness.‡

Immune defense

Most of your immune system lives in your gut. Keeping digestion balanced supports it every day.‡

Real people. Real results.

Good to aid in digestion. Sooo helpful.

Sometimes when I eat certain foods I feel bloated. When using this product, I've noticed I feel more comfortable after eating a meal.

Verified purchase —Jean Bailey Robor

Unbelievably fast results

I've been so uncomfortable due to bloating for months. This product has offered significant relief; my tummy no longer looks nor feels pregnant. I have been taking it about 4 days and I already feel better. Thank you for this solution!

Verified purchase —Yendi D.

Sooo helpful.

I'm in my mid-30's and I get bloated after I drink water… let alone eat anything. This has been a miracle to help me not look like a puffer fish like all time.

Verified purchase —christina lazzaro

Finally found something that works

I've always had trouble with bloating and breaking down my food. I saw this all over TikTok and decided to order it, and I was not disappointed. I highly suggest these.

Verified purchase —Tammy Hardenburg

No more heavy dinners

I take one with dinner and the difference is night and day. No more sitting on the couch afterwards feeling like a rock. Worth every penny.

Verified purchase —Marcus P.

Good to aid in digestion. Sooo helpful.

Sometimes when I eat certain foods I feel bloated. When using this product, I've noticed I feel more comfortable after eating a meal.

Verified purchase —Jean Bailey Robor

Unbelievably fast results

I've been so uncomfortable due to bloating for months. This product has offered significant relief; my tummy no longer looks nor feels pregnant. I have been taking it about 4 days and I already feel better. Thank you for this solution!

Verified purchase —Yendi D.

Sooo helpful.

I'm in my mid-30's and I get bloated after I drink water… let alone eat anything. This has been a miracle to help me not look like a puffer fish like all time.

Verified purchase —christina lazzaro

Finally found something that works

I've always had trouble with bloating and breaking down my food. I saw this all over TikTok and decided to order it, and I was not disappointed. I highly suggest these.

Verified purchase —Tammy Hardenburg

No more heavy dinners

I take one with dinner and the difference is night and day. No more sitting on the couch afterwards feeling like a rock. Worth every penny.

Verified purchase —Marcus P.
One capsule
Digestive enzymes

Amylase, protease, lipase, lactase and bromelain break down carbs, protein, fat and dairy before they can sit heavy.‡

Probiotic strains

Soil-based organisms chosen because they survive stomach acid and reach the gut intact.‡

Botanical blend

Organic ginger root and peppermint leaf to settle the stomach while the enzymes work.‡

Better digestion. Less discomfort. Every day.

Mealtime discomfort starts when your body can't fully break down food. Physician's Choice Digestive Enzymes support the digestion of proteins, fats, dairy and carbs so you can feel lighter, more comfortable and better after every meal.‡

Multi-enzyme digestive support

Advanced digestive enzyme blend

A diverse blend of 16 enzymes works in the stomach to help break down proteins, fats, dairy, carbs and veggies so no food is off the table.‡

Supports easier digestion

3-in-1 gut support system

3 Bacillus spore probiotic strains plus prebiotic fiber, with organic peppermint and ginger to settle the stomach.‡

Supports protein, carb & fat digestion‡ Helps reduce bloating‡ Non-GMO & third-party tested Doctor-developed formula◊
Support your digestion with confidence
60-day risk-free guarantee

Enzymes that work as hard as you do.

Beat the bloat

Feel lighter and more comfortable after meals without giving up the foods you love.‡

Eat without the aftermath

No more heavy, sluggish feeling after a big meal. Just dinner, the way it should be.‡

A Physician's Choice digestive enzyme capsule

Break down 5 food groups

16 enzymes tackle proteins, fats, dairy, carbs and veggies so nothing's off the menu.‡

Get more from every bite

Supports better nutrient absorption, so the food you eat actually works for you.‡

Beat the bloat today 60-day risk-free guarantee
A woman eating a salad at a table beside the Digestive Enzymes bottle and a bottle of water

How to take Digestive Enzymes

We've made it effortless to add Digestive Enzymes to your routine — no powders, no fuss, just one easy capsule.

Take 1 capsule with your meal. Before, during or after — whatever's easiest.‡

Pair with water. Easy to swallow, no aftertaste. No refrigeration needed.

Eat more? Take more. Add another capsule for bigger meals or trigger foods.‡

26 cents a day vs. what mealtime discomfort actually costs you

Here's the real math on chasing digestive relief one fix at a time.

Physician's Choice Digestive Enzymes
About 26 cents a day on the 180-count 16 enzymes in a single capsule 3 spore strains that survive stomach acid Prebiotic fiber, same capsule Peppermint and ginger to settle things Works at the meal, not hours later Subscribe and save up to 25% 60-day money-back guarantee
Everything else you've tried
A probiotic alone: the meal still sits there A single-enzyme pill: one food group only Refrigerated probiotics: $30+ a bottle Antacids: masking it, every single time Cutting out food after food after food A GI copay for 'keep a food diary': $40 Months of trial and error, nothing changes Still bloated after dinner
Get Digestive Enzymes → About a quarter a day to start enjoying meals again.
A hand reaching for a Digestive Enzymes bottle and a glass of water on a stack of books
Our product quality

We hold our digestive support to a higher standard

Every Physician’s Choice formula is reviewed by our advisory board of gastroenterologists, naturopathic doctors and functional-medicine nutritionists before it ever reaches a bottle.◊

A full-spectrum enzyme blend plus shelf-stable Bacillus spore strains and the prebiotic fiber that feeds them — three jobs, one capsule, no stacking required.

Every lot of every product is tested for purity and potency at ISO/IEC 17025-accredited labs, the international standard for testing-lab competence.

No artificial colors, flavors, sweeteners or preservatives. No GMOs, no dairy or soy, and no unnecessary fillers or binders.

Try risk-free today 60-day money-back guarantee
Honest answers

Your questions, answered.

A probiotic only adds beneficial bacteria. This pairs 3 shelf-stable probiotic strains with 16 digestive enzymes, prebiotic fibers to feed those bacteria, and organic peppermint and ginger. Think of it less as a probiotic and more as a complete digestive support system.

Yes. The serving is 1 capsule with your largest meal, but many people take an extra one with other heavy meals. Most don't exceed 2 a day. If you'd like to take more than that regularly, check with your healthcare provider.

Because the enzymes are meant to start working in your stomach. A delayed-release shell would bypass the exact window where they do their best work. The probiotics are protected differently — spore-forming Bacillus strains are naturally acid-resistant.

Yes, both. The capsule is plant-based hypromellose, the enzymes are microbial and plant-derived — bromelain from pineapple, papain from papaya — and every other ingredient is plant-sourced.

Yes. It's designed for daily, ongoing use and is not habit-forming. Many customers take it daily for years.

Speak with your healthcare provider first. They know your full health picture and can advise what's right for you.

About 2 years from the date of manufacture — the exact date is printed on the bottom of your bottle. Store somewhere cool and dry; a kitchen cabinet beats the bathroom, where shower humidity can shorten shelf life.

Our 60 Billion Probiotic and Digestive Enzymes contain inulin, and our Fiber Gummies contain chicory root fiber; gut bacteria break down fibers like these, which can cause gas. If you have known allergies, review the product’s ingredient list and allergen information and consult your healthcare provider before purchasing or using it. Most of our products are formulated without the top 9 common allergens, but ingredients vary by product.

Still deciding?

Every order is covered for 60 days. Finish the bottle, and if your meals aren't sitting better, we'll refund you.

Talk to our team

Eat everything.
Regret nothing.

Bloating, heaviness and post-meal regret start when your body can't fully break down what you're eating. Physician's Choice Digestive Enzymes pack 16 enzymes, 3 probiotic strains and prebiotic fiber into one easy capsule so you can dig in without the aftermath.‡

Make every meal better
Third-party tested Developed with doctors◊ 60-day money-back guarantee
Digestive Enzymes bottle and carton on turf beside wings, chips and salsa