Organic C3 Turmeric Curcumin & Boswellia Extract

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C3® Turmeric Curcumin & Boswellia Serrata Extract

We've combined proven natural and organic ingredients at efficacious doses to provide mobility, joint support, and fight inflammation. C3 Curcumin extract is a patented & award winning turmeric standardized to 95% Curcuminoids. C3 Curcumin is the #1 most clinically studied turmeric on the market with over 65 scientific publications.   

Research has found that 65% Boswellia serrata extracts have been beneficial to joint health and movement. Multiple studies have found that Turmeric in combination with Boswellia is more effective than turmeric alone or even NSAID.

To enhance bioavailability (absorption) we've included patented Bioperine® a black pepper extract shown to increase nutrient absorption up to 2000%. 

Buyer Beware! Read Supplement Facts Carefully  

C3 Turmeric Curcumin Complex

Turmeric and Boswellia's therapeutic benefits come from what is known as "active compounds" of 95% Curcuminoids and 65% Boswellia Serrata. 

The majority of supplement manufacturers are cutting corners by either not using standardized extracts or, more commonly, sprinkling in only trace amounts of 95% Curcuminoids. 

Standardized extracts deliver a guaranteed concentration of the active compound in every dose. Simply put, you're getting the therapeutic benefits you paid for in every dose.

Our Turmeric-Boswellia blend contains the highest standardized extracts available with 100mgs of Boswellia Serrata standardized to 65% and 500mgs of Turmeric Curcumin standardized to 95% Curcuminoids.
C3 Turmeric Curcumin Complex Boswellia

The Physician's Choice Difference 

  • Patented Award Winning -C3 Turmeric Curcumin Complex
  • Standardized 500mgs of 95% Curcuminoids
  • C3 Curcumin 65+ Clinical Trials validate its effectiveness
  • Boswellia Serrate Extract Standardized 65%
  • Turmeric Curcumin + Boswellic Serrate
  • Bioperine® is clinically proven to increase absorption by up to 2000%
  • Organic Turmeric Root
  • Organic Ginger
  • Non-GMO / Gluten-free / Vegan

Natural Joint Support Backed by Science 

Boswellia & Turmeric Curcumin - Studies have found that two of nature’s most powerful herbs — turmeric and Boswellia serrata — can often help with strengthening and protecting joint health.

One study published in Phytotherapy Research involved 45 patients with (RA), some of whom took curcumin, some of whom took a non-steroidal anti-inflammatory drug (NSAID), and some of whom took both. Though all groups reported “significant changes” in their joint tenderness and swelling, the individuals who took curcumin Boswellia combination had the most favorable results.

C3 Curcumin Complex has over 65 published studies and clinical evidence supporting its many benefits back to 1998.

 

Turmeric Curcumin Supplement

 

C3® Turmeric Curcumin & Boswellia Serrata Extract

We've combined proven natural and organic ingredients at efficacious doses to provide mobility, joint support, and fight inflammation. C3 Curcumin extract is a patented & award winning turmeric standardized to 95% Curcuminoids. C3 Curcumin is the #1 most clinically studied turmeric on the market with over 65 scientific publications.   

Research has found that 65% Boswellia serrata extracts have been beneficial to joint health and movement. Multiple studies have found that Turmeric in combination with Boswellia is more effective than turmeric alone or even NSAID.

To enhance bioavailability (absorption) we've included patented Bioperine® a black pepper extract shown to increase nutrient absorption up to 2000%. 

Buyer Beware! Read Supplement Facts Carefully  

C3 Turmeric Curcumin Complex

Turmeric and Boswellia's therapeutic benefits come from what is known as "active compounds" of 95% Curcuminoids and 65% Boswellia Serrata. 

The majority of supplement manufacturers are cutting corners by either not using standardized extracts or, more commonly, sprinkling in only trace amounts of 95% Curcuminoids. 

Standardized extracts deliver a guaranteed concentration of the active compound in every dose. Simply put, you're getting the therapeutic benefits you paid for in every dose.

Our Turmeric-Boswellia blend contains the highest standardized extracts available with 100mgs of Boswellia Serrata standardized to 65% and 500mgs of Turmeric Curcumin standardized to 95% Curcuminoids.
C3 Turmeric Curcumin Complex Boswellia

The Physician's Choice Difference 

  • Patented Award Winning -C3 Turmeric Curcumin Complex
  • Standardized 500mgs of 95% Curcuminoids
  • C3 Curcumin 65+ Clinical Trials validate its effectiveness
  • Boswellia Serrate Extract Standardized 65%
  • Turmeric Curcumin + Boswellic Serrate
  • Bioperine® is clinically proven to increase absorption by up to 2000%
  • Organic Turmeric Root
  • Organic Ginger
  • Non-GMO / Gluten-free / Vegan

Natural Joint Support Backed by Science 

Boswellia & Turmeric Curcumin - Studies have found that two of nature’s most powerful herbs — turmeric and Boswellia serrata — can often help with strengthening and protecting joint health.

One study published in Phytotherapy Research involved 45 patients with (RA), some of whom took curcumin, some of whom took a non-steroidal anti-inflammatory drug (NSAID), and some of whom took both. Though all groups reported “significant changes” in their joint tenderness and swelling, the individuals who took curcumin Boswellia combination had the most favorable results.

C3 Curcumin Complex has over 65 published studies and clinical evidence supporting its many benefits back to 1998.

 

Turmeric Curcumin Supplement

 

Manufacturing & Sourcing:

Physician’s Choice products are manufactured in the USA in a cGMP FDA & Organic certified facility.

Raw materials are acquired through industry best practices. This includes patented and IP backed ingredients from world-renowned health science companies,  implementation of stringent testing methods that include HPTLC, HPLC and other industry-leading tests throughout processing and preparation of the finished product.

All ingredients sourced must pass multi-step quality control processing conducted by qualified scientists and technicians using advanced techniques to assure transparency, purity, and safety.

Each stage of product journey is documented and verified from harvesting to packaging, guaranteeing the safest, most effective product possible.

Tumeric is a plant that provides various health benefits due to its active components called curcuminoids. Research shows that curcuminoids help reduce the risk of having a heart attack by improving the circulatory system’s ability to regulate blood clotting and blood pressure [1]. Curcuminoids are also able to pass through the blood-brain barrier, where they protect brain cells from oxidative damage, inflammation, and protein buildup (amyloid plaques) that is linked to the onset of Alzheimer’s disease [2, 3]. Furthermore, ample research has been conducted on turmeric’s primary curcuminoid called curcumin.

This particular nutrient has potent antioxidant and anti-inflammatory properties, which have been shown to disrupt various stages of inflammation [4-6]. More specifically, curcumin hinders the activity of inflammatory proteins that can travel into the body’s cells and activate genes that trigger inflammation [7, 8]. Furthermore, curcumin’s anti-inflammatory properties are so strong that it dramatically improves processes in the body assist in the prevention of cardiovascular, neurodegenerative, metabolic, neoplastic, autoimmune, and pulmonary diseases [9-13].

In addition, curcumin has the capacity to target free radicals (toxins) and it also enhances the activity of antioxidant enzymes the body naturally produces [14-18]. Curcumin further boosts brain health by enhancing the production of a growth hormone called brain-derived neurotrophic factor (BDNF) that plays a role in the formation of neurons in the brain and new neuronal connections [19, 20]. By boosting the levels of BDNF, curcumin heightens mental function (e.g. concentration, memory) and the body’s ability to reverse or delay age-related cognitive impairments as well as different types of brain diseases [21, 22].

Additionally, curcumin demonstrates anti-cancer properties through its capacity to hinder the growth, development, and metastasis (spread) of cancer cells [23, 24]. More specifically, it disrupts the growth of new blood vessels in tumors, thereby hindering metastasis and promoting the death of cancer cells, especially cancerous cells in the colon [25-27]. Research also shows that curcumin can reduce the number of precancerous lesions that can potentially differentiate into cancerous tumors [27]. This means curcumin improves bodily processes that prevent the onset or progression of various diseases, including those that are age-related [28-30].

Curcumin is safely and quickly absorbed into the bloodstream, but according to research, combining it with Bioperine improves its absorption by approximately 2000% [31]. Bioperine, which is also known as piperine, is an extract from black pepper that is well known for its ability to dramatically enhance the body’s absorption of other nutrients [32]. However, this potent mineral also targets joint and muscle pain as well as bronchitis, Parkinson’s disease, and heart disease through its ability to disrupt inflammatory and plaque-forming processes [32-38].

In addition to these benefits, Bioperine is frequently combined with other vitamins, herbs, and minerals because it safely increases the bioavailability of essential nutrients [31, 34]. For instance, consuming Bioperine regularly enhances the levels of selenium, B vitamins, and vitamin C that the body extracts from food [32]. It also boosts metabolism by improving nutrient absorption in the digestive tract and the bloodstream [31]. Therefore, the combination of Bioperine and the curcuminoids in turmeric can dramatically improve overall health when they are taken regularly.

References

1.        Wongcharoen W, Jai-Aue S, Phrommintikul A, Nawarawong W, Woragidpoonpol S, Tepsuwan T, Sukonthasarn A, Apaijai N, Chattipakorn N. Effects of curcuminoids on frequency of acute myocardial infarction after coronary artery bypass grafting. Am J Cardiol. 2012;110(1):40-4.

2.        Mishra S, Palanivelu K. The effect of curcumin (turmeric) on Alzheimer's disease: An overview. Ann Indian Acad Neurol. 2008;11(1):13-9.

3.        Zhang L, Fiala M, Cashman J, Sayre J, Espinosa A, Mahanian M, Zaghi J, Badmaev V, Graves MC, Bernard G, Rosenthal M. Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer's disease patients. J Alzheimers Dis. 2006;10(1):1-7.

4.        Nagpal M, Sood S. Role of curcumin in systemic and oral health: An overview. J Nat Sci Biol Med. 2013; 4(1): 3–7.

5.        Tayyem RF, Heath DD, Al-Delaimy WK, Rock CL. Curcumin content of turmeric and curry powders. Nutr Cancer. 2006;55(2):126-31.

6.        Jurenka JS. Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Altern Med Rev. 2009;14(2):141-53.

7.        SinghS, Aggarwal BB. Activation of Transcription Factor NF-κB Is Suppressed by Curcumin (Diferuloylmethane). J Bio  Chem. 1995; 270:24995-25000.

8.        Marín YE, Wall BA, Wang S, Namkoong J, Martino JJ, Suh J, Lee HJ, Rabson AB, Yang CS, Chen S, Ryu JH. Curcumin downregulates the constitutive activity of NF-kappaB and induces apoptosis in novel mouse melanoma cells. Melanoma Res. 2007;17(5):274-83.

9.        Chainani-Wu N. Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). J Altern Complement Med. 2003 Feb;9(1):161-8.

10.        Goel A, Boland CR, Chauhan DP. Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells. Cancer Lett. 2001;172(2):111-8.

11.        Aggarwal BB, Harikumar KB. Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. Int J Biochem Cell Biol. 2009;41(1):40-59.

12.        Lal B, Kapoor AK, Asthana OP, Agrawal PK, Prasad R, Kumar P, Srimal RC. Efficacy of curcumin in the management of chronic anterior uveitis. Phytother Res. 1999 Jun;13(4):318-22.

13.        Takada Y, Bhardwaj A, Potdar P, Aggarwal BB. Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D, and abrogation of tumor cell proliferation. Oncogene. 2004;23(57):9247-58.

14.        Menon VP1, Sudheer AR.Antioxidant and anti-inflammatory properties of curcumin. Adv Exp Med Biol. 2007;595:105-25.

15.        Barclay LR, Vinqvist MR, Mukai K, Goto H, Hashimoto Y, Tokunaga A, Uno H. On the antioxidant mechanism of curcumin: classical methods are needed to determine antioxidant mechanism and activity. Org Lett. 2000;2(18):2841-3.

16.        Agarwal R, Goel SK, Behari JR. Detoxification and antioxidant effects of curcumin in rats experimentally exposed to mercury. J Appl Toxicol. 2010;30(5):457-68.

17.        Bulmus FG, Sakn F, Turk G, Sonmez M, Servi K. Protective effects of curcumin on antioxidant status, body weight gain, and reproductive parameters in male rats exposed to subchronic 2,3,7,8-tetrachlorodibenzo-p-dioxin. Tox Envir Chem. 2013; 95(6):1019-1029.

18.        Biswas SK, McClure D, Jimenez LA, Megson IL, Rahman I. Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. Antioxid Redox Signal. 2005;7(1-2):32-41.

19.        Xu Y, Ku B, Tie L, Yao H, Jiang W, Ma X, Li X. Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB. Brain Res. 2006;1122(1):56-64.

20.        Hurley LL, Akinfiresoye L, Nwulia E, Kamiya A, Kulkarni AA, Tizabi Y. Antidepressant-like effects of curcumin in WKY rat model of depression is associated with an increase in hippocampal BDNF. Behav Brain Res. 2013;239:27-30.

21.        Dong S, Zeng Q, Mitchell ES, Xiu J, Duan Y, Li C, Tiwari JK, Hu Y, Cao X, Zhao Z. Curcumin enhances neurogenesis and cognition in aged rats: implications for transcriptional interactions related to growth and synaptic plasticity. PLoS One. 2012;7(2):e31211.

22.        Belviranlı M, Okudan N, Atalık KE, Öz M. Curcumin improves spatial memory and decreases oxidative damage in aged female rats. Biogerontology. 2013;14(2):187-96.

23.        Aggarwal BB, Kumar A, Bharti AC. Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res. 2003;23(1A):363-98.

24.        Anand P, Sundaram C, Jhurani S, Kunnumakkara AB, Aggarwal BB. Curcumin and cancer: an "old-age" disease with an "age-old" solution. Cancer Lett. 2008;267(1):133-64.

25.        Ravindran J, Prasad S, Aggarwal BB. Curcumin and cancer cells: how many ways can curry kill tumor cells selectively? AAPS J. 2009;11(3):495-510.

26.        Kawamori T, Lubet R, Steele VE, Kelloff GJ, Kaskey RB, Rao CV, Reddy BS. Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer. Cancer Res. 1999;59(3):597-601.

27.        Carroll RE, Benya RV, Turgeon DK, Vareed S, Neuman M, Rodriguez L, Kakarala M, Carpenter PM, McLaren C, Meyskens FL Jr, Brenner DE. Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia. Cancer Prev Res (Phila). 2011;4(3):354-64.

28.        Sikora E, Scapagnini G, Barbagallo M. , inflammation, ageing and age-related diseases. Immun Ageing. 2010;7(1):1.

29.        Sikora E, Bielak-Zmijewska A, Mosieniak G, Piwocka K. The promise of slow down ageing may come from curcumin. Curr Pharm Des. 2010;16(7):884-92.

30.        Chandran B, Goel A. A randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritis. Phytother Res. 2012;26(11):1719-25.

31.        Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998;64(4):353-6.

32.        McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

33.        Umar S, Golam Sarwar AH, Umar K, Ahmad N, Sajad M, Ahmad S, Katiyar CK, Khan HA. Piperine ameliorates oxidative stress, inflammation and histological outcome in collagen induced arthritis. Cell Immunol. 2013; 284(1-2):51-9.

34.        Bano G, Amla V, Raina RK, et al. The effect of piperine on pharmacokinetics of phenytoin in healthy volunteers. Planta Med 1987;53:568-9.

35.        Khardwaj RK, Glaeser H, Becquemont L, et al. Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4. J Pharmacol Exp Ther 2002;302:645-50.

36.        Prakash UN, Srinivasan K. Gastrointestinal protective effect of dietary spices during ethanol-induced oxidant stress in experimental rats. Appl Physiol Nutr Metab. 2010 Apr;35(2):134-41

37.        Diwan V, Poudyal H, Brown L. Piperine attenuates cardiovascular, liver and metabolic changes in high carbohydrate, high fat-fed rats. Cell Biochem Biophys. 2013;67(2):297-304. 

38.        Shrivastava P, Vaibhav K, Tabassum R, et al.  Anti-apoptotic and anti-inflammatory effect of Piperine on 6-OHDA induced Parkinson's rat model. J Nutr Biochem. 2013;24(4):680.

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    Reviews

    Customer Reviews

    4.9 Based on 1091 Reviews
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    Your input is very much appreciated. Share it with your friends so they can enjoy it too!

    AC
    08/29/2019
    Amazon Customer

    RA + Lupus Pain

    I have rheumatoid arthritis and it has helped with joint pain.

    LS
    08/29/2019
    Linds S.

    Turmeric is great for a lot of health benefits!

    I have been curious about turmeric for a while, after my mom has suggested I take it because she’s seen a lot of health benefits since she started a regimen of turmeric. These came nicely packaged, and they are not too large. I was a little worried about a taste while swallowing it, but there is none, and I don’t feel yucky after taking it either. Great product, and I definitely recommend this brand.

    M
    08/29/2019
    MEC

    Best Turmeric I’ve tried

    25 years after reconstructive knee surgery, scar tissue and arthritis have caused daily pain in BOTH knees. Taking this turmeric w/ Boswellia supplement has drastically reduced this pain, and done so better than other turmeric supplements I’ve taken in the past. I’ve also noticed my back pain much less over the last several weeks

    AC
    08/28/2019
    Amazon Customer

    Includes Bioperine, Boswellia and Ginger

    I have used Turmeric with Bioperine for many years to successfully keep joint pain at bay. This brand, with the added Boswellia and Ginger has lived up to my expectations.

    IC
    08/28/2019
    Irene Chouljenko

    Great product!

    After taking the vitamins, I feel less stiff. I feel that its easier going down the stairs.